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Without its protection, one can reasonably expect a diminished useful lifespan in many of the critical tissues which are necessary to support normal homeostasis

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We discussed specific dietary sources and pharmacokinetics of selected compounds, providing insights into their bioavailability and potential synergistic effects with conventional therapies

[PMC free article: PMC3413219] [PubMed: 22665167] 423

2.2.4 Roles of defensins in abiotic stresses 2.2.4.1 Defensin-mediated mechanisms for heavy metal tolerance A primary mechanism for heavy metal tolerance is the chelation of metal ions by the cysteine-rich domains of defensins, followed by the efflux of the metal-defensin complex from the cytoplasm to less sensitive extracellular compartments like cell walls or the apoplast, or into vascular tissues for transport (Luo et al., 2018